Regions | 495/MetroWest

The 495/MetroWest region covers the area stretching along I-495 from Route 2 in the north to Route 1 in the south. As the home to many of Massachusetts’s largest and fastest growing companies, the region is at the forefront of the state’s innovation economy. Companies including GE Healthcare Life Sciences, EBose, EMC, Cisco, IBM, and Genzyme are located in this economically vibrant area of Massachusetts.

The region is home to over 608,000 people. The employers located in the 495/MetroWest Corridor provide a total of more than 326,000 jobs, representing one out of every eleven jobs in the state, and have a combined payroll of $22.5 billion dollars, which represents one out of every ten payroll dollars in Massachusetts. The region has a robust and diverse economy across several different employment sectors.

To find out about the business services available in the MetroWest click here.

Competitive Advantages

Business Network

The MetroWest region has taken a leading role in Massachusetts with an emphasis on innovation within technologies, practices, and approaches. The MetroWest region is home to the headquarters and major facilities of six of the largest employers in Massachusetts: Boston Scientific, EMC, Genzyme, Raytheon, Staples, and TJX.

Transportation Infrastructure

The Massachusetts Turnpike traverses the region east-west, allowing for access to Boston or Western Massachusetts; Interstate 495 runs north-south through the region while Route 128/Interstate 95 also runs north-south along the region’s eastern edge. Much of the region is accessible to direct commuter rail service into Boston. Recently, a regional transit agency was created to provide public transit connections within the region.


One of the top competitive strengths in the region is the quality of the skilled workforce. More than 56% of the population’s region holds a bachelor’s degree or higher compared with 40% nationwide; this presence of technically skilled and innovative workers has directly contributed to the rise in the MetroWest’s economic strength.